HCID 11608988, compound → HCID 68776278, compound

HRID 2263501Notes

Reaction equation

HRID 2263501 reaction equation
[F:1][C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[CH:6][CH:5]=[CH:4][C:3]=1[C:12]1(O)[CH2:17][CH2:16][N:15]([CH2:18][CH3:19])[CH2:14][CH2:13]1>Cl>[F:1][C:2]1[C:7]([C:8]([F:9])([F:10])[F:11])=[CH:6][CH:5]=[CH:4][C:3]=1[C:12]1[CH2:17][CH2:16][N:15]([CH2:18][CH3:19])[CH2:14][CH:13]=1

Participants

3

Reactant 1

HCID 11608988HCID 11608988, compound

Product 1

HCID 68776278HCID 68776278, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

Preparation according to preparation 4: 4-[2-fluoro-3-(trifluoromethyl)phenyl]-1-ethylpiperidin-4-ol (3.3 g, 11.3 mmol), hydrochloric acid (10 ml, conc). Yield: 3.1 g. MS m/z (rel. intensity, 70 eV) 273 (M+, 65), 272 (32), 258 (bp), 147 (24), 110 (22).

Workup

  1. customPreparation
  2. customaccording to preparation 4

Sources & evidence

ORD record
ord-0619e9b50eba4ec9890681024abd61a7
Source dataset
uspto-grants-2010_12
Patent number
US07851629B2

Reaction notes

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