HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 67071323, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-[2-(1,1-Dioxo-isothiazolidin-2-yl)-ethyl]-piperazine-1-carboxylic acid tert-butyl ester | HCID 57566070 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 67071323 | HCID 67071323 | — |
Reaction Steps
4-[2-(1,1-Dioxo-isothiazolidine-2-yl)-ethyl]-piperazine-1-carboxylic acid tert-butyl ester (2.01 g) was treated with 30% trifluoroacetic acid in dichloromethane (10 mL), and the mixture was stirred at room temperature for 30 min. The mixture was concentrated in vacuo to give 2.46 g of 1-[2-(1,1-dioxo-isothiazolidine-2-yl)-ethyl]-piperazine trifluoroacetate as a solid. LR-MS: 234 [(M+H)+]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07851626B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-4f1c946cc44f40a3a2b584f527a9c5a7 |
| Source note | uspto-grants-2010_12 |