反应详情

4-[2-(1,1-Dioxo-isothiazolidine-2-yl)-ethyl]-piperazine-1-carboxylic acid tert-butyl ester (2.01 g) was treated with 30% trifluoroacetic acid in dichloromethane (10 mL), and the mixture was stirred at room temperature for 30 min. The mixture was concentrated in vacuo to give 2.46 g of 1-[2-(1,1-dioxo-isothiazolidine-2-yl)-ethyl]-piperazine trifluoroacetate as a solid. LR-MS: 234 [(M+H)+]

1. concentrationThe mixture was concentrated in vacuo