Ammonia → HCID 59595967, compound

HRID 2264188Notes

Reaction equation

HRID 2264188 reaction equation
CO[C:3]1[C:8]([N+:9]([O-:11])=[O:10])=[CH:7][CH:6]=[C:5]([C:12]2[O:13][CH:14]=[CH:15][N:16]=2)[N:4]=1.[NH3:17]>>[N+:9]([C:8]1[C:3]([NH2:17])=[N:4][C:5]([C:12]2[O:13][CH:14]=[CH:15][N:16]=2)=[CH:6][CH:7]=1)([O-:11])=[O:10]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 59595975HCID 59595975, compound

Product 1

HCID 59595967HCID 59595967, compoundYield 77%

Conditions

Temperature
100 °C

Procedure

A suspension of 2-methoxy-3-nitro-6-(1,3-oxazol-2-yl)pyridine (0.187 g, 0.85 mmol) in aqueous ammonia (32%, 5 mL) was heated in a sealed tube to 100° C. with stirring. After 2.5 hours the mixture was cooled and the precipitate was filtered and washed with water and then dried in vacuo to give the title compound (0.134 g, 77%) as a yellow solid.

Workup

  1. temperatureAfter 2.5 hours the mixture was cooled
  2. filtrationthe precipitate was filtered
  3. washwashed with water
  4. customdried in vacuo

Sources & evidence

ORD record
ord-bade95ccfb0740ec8e7645ffadde844b
Source dataset
uspto-grants-2010_12
Patent number
US07855202B2

Reaction notes

Loading…