Diisopropylcarbodiimide → HCID 178505989, compound

HRID 2264205Notes

Reaction equation

[F:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[C:8]1[C:9]([C:16]2[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=2)=[N:10][C:11]([NH2:15])=[C:12]([NH2:14])[CH:13]=1.[Cl:22][C:23]1[CH:28]=[CH:27][C:26]([N:29]=[C:30]=S)=[CH:25][CH:24]=1.C(N=C=NC(C)C)(C)C>C(O)C>[Cl:22][C:23]1[CH:28]=[CH:27][C:26]([NH:29][C:30]2[NH:15][C:11]3=[N:10][C:9]([C:16]4[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=4)=[C:8]([C:7]4[CH:6]=[CH:5][N:4]=[CH:3][C:2]=4[F:1])[CH:13]=[C:12]3[N:14]=2)=[CH:25][CH:24]=1

Participants

Conditions

Temperature: 50 °C

Procedure

To a solution of 3″-fluoro-3,2′:3′,4″-terpyridine-5′,6′-diamine (Intermediate 1, 0.050 g, 0.179 mmol) and 1-chloro-4-isothiocyanatobenzene (0.045 g, 0.267 mmol) in ethanol (1 mL), 1,3-diisopropylcarbodiimide (0.042 mL, 0.267 mmol) was added. The mixture was heated at 50° C. for 2 h. After cooling at room temperature, the solid precipitated was filtered off to give the title compound (0.035 g, 47% of yield).

Workup

temperatureAfter cooling at room temperature
customthe solid precipitated
filtrationwas filtered off

Sources & evidence

ORD record: ord-2bfff74fea864ad7b8ff017b4dec5d9c
Source dataset: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07855202B2

Reaction notes

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