4-Aminotetrahydropyran → HCID 56663232, compound

Participants

Reaction Steps

Using the procedure of example 1, tetrahydropyran-4-ylamine (0.8 g) was reacted with compound 1f (1.8 g) to provide compound 60 (1.2 g, 42%). 1H NMR (400 MHz, DMSO) δ 12.20 (s, 1H), 8.95 (s, 1H), 8.39 (s, 1H), 8.30 (d, 1H), 8.15 (d, 1H), 7.20 (m, 1 H), 7.06 (d, 1H), 7.04 (d, 1H), 4.00 (m, 1H), 3.90 (m, 2H), 3.45 (m, 2H), 1.90 (m, 2 H), 1.55 (m, 2H).

Provenance & Evidence