9-Methyl-3,9-diazabicyclo[3.3.1]nonane → HCID 68647616, compound

HRID 2264278Notes

Reaction equation

HRID 2264278 reaction equation
[CH3:1][N:2]1[CH:7]2[CH2:8][CH2:9][CH2:10][CH:3]1[CH2:4][NH:5][CH2:6]2.[N+:11]([C:14]1[CH:19]=[CH:18][C:17]([C:20]2[O:24][C:23]([C:25]([Cl:27])=[O:26])=[CH:22][CH:21]=2)=[CH:16][CH:15]=1)([O-:13])=[O:12]>COCCOC>[ClH:27].[CH3:1][N:2]1[CH:7]2[CH2:8][CH2:9][CH2:10][CH:3]1[CH2:4][N:5]([C:25]([C:23]1[O:24][C:20]([C:17]3[CH:16]=[CH:15][C:14]([N+:11]([O-:13])=[O:12])=[CH:19][CH:18]=3)=[CH:21][CH:22]=1)=[O:26])[CH2:6]2

Participants

4

Reactant 2

HCID 189119-Methyl-3,9-diazabicyclo[3.3.1]nonaneHCID 38299835-(4-nitrophenyl)furan-2-carbonyl Chloride

Product 1

HCID 68647616HCID 68647616, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

9-Methyl-3,9-diaza-bicyclo[3.3.1]nonane (2.0 g, 14.3 mmol), 5-(4-nitro-phenyl)-furan-2-carboxylic acid chloride (3.59 g, 14.3 mmol) and 1,2-dimethoxyethane (40 ml) was stirred at room temperature for 15 hours. The product was filtered and was purified by washing with 1,2-dimethoxyethane (100 ml). Yield 5.24 g (94%). Mp. 263° C.

Workup

  1. filtrationThe product was filtered
  2. customwas purified
  3. washby washing with 1,2-dimethoxyethane (100 ml)

Sources & evidence

ORD record
ord-278b2934e4d1495a918b5a06a807af14
Source dataset
uspto-grants-2010_12
Patent number
US07855208B2

Reaction notes

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