HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 178478386, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,4-Dichloroquinazoline | HCID 252886 | — |
| Reactant | 5-Cyclopentyl-1H-pyrazol-3-amine | HCID 22176827 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178478386 | HCID 178478386 | 66.1% |
Reaction Steps
2,4-Dichloroquinazoline (0.657 g, 3.3 mmol) in ethanol (9 ml) was treated with 3-amino-5-cyclopentyl pyrazole (0.5 g, 3.3 mmol) and triethylamine (0.46 ml, 3.3 mmol) and stirred overnight at room temperature. The mixture was filtered and the solid washed with ethanol to give (2-chloro-quinazolin-4-yl)-(5-cyclopentyl-2H-pyrazol-3-yl)-amine as colourless crystals (684 mg, 66%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07855214B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-9144ac6f143e4a6986c6144f63eb7a7c |
| Source note | uspto-grants-2010_12 |