Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2264381Generated: October 30, 2026

Triethylamine → HCID 178478386, compound

https://huagongshe.com/reaction/2264381

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
Reactant2,4-DichloroquinazolineHCID 252886—
Reactant5-Cyclopentyl-1H-pyrazol-3-amineHCID 22176827—
SolventEthanolHCID 702—
ProductHCID 178478386HCID 17847838666.1%

Reaction Steps

2,4-Dichloroquinazoline (0.657 g, 3.3 mmol) in ethanol (9 ml) was treated with 3-amino-5-cyclopentyl pyrazole (0.5 g, 3.3 mmol) and triethylamine (0.46 ml, 3.3 mmol) and stirred overnight at room temperature. The mixture was filtered and the solid washed with ethanol to give (2-chloro-quinazolin-4-yl)-(5-cyclopentyl-2H-pyrazol-3-yl)-amine as colourless crystals (684 mg, 66%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07855214B2
Source datasetuspto-grants-2010_12
ORD IDord-9144ac6f143e4a6986c6144f63eb7a7c
Source noteuspto-grants-2010_12