Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-cyclopropyl-1H-pyrazol-5-amine | HCID 2758014 | — |
| Reactant | HCID 68521080 | HCID 68521080 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178478382 | HCID 178478382 | — |
Reaction Steps
2,4-Dichloro-1,2,5,6,7,8-hexahydro-quinazoline (1 g, 4.93 mmol) and 3-amino-5-cyclopropylpyrazole (0.606 g, 4.93 mmol) in ethanol (8 ml) was treated with triethylamine (1.24 ml, 8.87 mmol) and the mixture heated at 120° C. for 3 days, cooled and filtered to give (0.72 g, 51%) as a colourless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07855214B2 |
|---|
| Source dataset | uspto-grants-2010_12 |
|---|
| ORD ID | ord-b6f50a9f5af0470e933f4cdd969b9969 |
|---|
| Source note | uspto-grants-2010_12 |
|---|
