Hydrochloric Acid → HCID 68781860, compound

Participants

Reaction Steps

A solution of 4-(4,6-dimethoxy-pyrimidin-2-ylamino)-piperidine-1-carboxylic acid tert-butyl ester (1.97 g, 5.82 mmol) in ethanol (50 mL) and 4 M HCl in dioxane (75 mL) was stirred at rt for 2 h. The solvent was removed under reduced pressure and the crude product used in the consecutive step without further purification assuming quantitative deprotection and formation of the dihydrochloride salt. MS (ISP): 239.1 [M+H]+.

Provenance & Evidence