Hydrochloric Acid → HCID 86615297, compound

Participants

Reaction Steps

A solution of 4-(8-amino-[1,3]dioxolo[4,5-g]quinazolin-6-ylamino)-piperidine-1-carboxylic acid tert-butyl ester (0.6 g, 1.55 mmol) in ethanol (5 mL) and 4 M HCl in dioxane (20 mL) was stirred at rt for 2 h. The solvent was removed under reduced pressure and the crude product used in the consecutive step without further purification assuming quantitative deprotection and formation of the dihydrochloride salt. MS (ESI): 288.4 [M+H]+.

Provenance & Evidence