Benzoyl Peroxide → HCID 59596843, compound

HRID 2264667Notes

Reaction equation

HRID 2264667 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[O:9][CH2:10][C:11]([F:14])([F:13])[F:12].C1C(=O)N([Br:22])C(=O)C1.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:22][CH2:8][C:5]1[CH:6]=[CH:7][C:2]([F:1])=[C:3]([O:9][CH2:10][C:11]([F:13])([F:12])[F:14])[CH:4]=1

Participants

5

Reactant 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 59596825HCID 59596825, compound

Product 1

HCID 59596843HCID 59596843, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

A mixture of 2.68 g (12.8 mmol) of 1-fluoro-4-methyl-2-(2,2,2-trifluoro-ethoxy)-benzene, 2.3 g (12.9 mmol) of NBS and 140 mg of dibenzoylperoxide in 60 ml of CCl4 was refluxed for 6 hours. Solvent was removed and the crude residue was used without any further purification for the next step.

Workup

  1. temperaturewas refluxed for 6 hours
  2. customSolvent was removed
  3. customthe crude residue was used without any further purification for the next step

Sources & evidence

ORD record
ord-323e61adc1594912b0f0f38b09f4e05f
Source dataset
uspto-grants-2010_12
Patent number
US07855227B2

Reaction notes

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