Hydrazine → HCID 136339049, compound

HRID 2264851Notes

Reaction equation

HRID 2264851 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:10]=[C:9]([CH:11]=O)[NH:8][C:7]=1[CH3:13])=[O:5])[CH3:2].[NH2:14][NH2:15]>CCO>[CH2:1]([O:3][C:4]([C:6]1[CH:10]=[C:9]([CH:11]=[N:14][NH2:15])[NH:8][C:7]=1[CH3:13])=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 255661ethyl 5-formyl-2-methyl-1h-pyrrole-3-carboxylate

Product 1

HCID 136339049HCID 136339049, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 5-formyl-2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester (6.30 g, 0.034 mol) in EtOH (6.3 mL) was added a solution of hydrazine (1.69 mL, 0.034 mol). The reaction mixture was stirred at RT overnight. The resulting precipitate was filtered and dried in vacuo to give the titled compound, 6.79 g as a light yellow solid. This material was used without further purification.

Workup

  1. filtrationThe resulting precipitate was filtered
  2. customdried in vacuo

Sources & evidence

ORD record
ord-67d28d0de2f54c36a9a311e0ccb97d94
Source dataset
uspto-grants-2010_12
Patent number
US07855288B2

Reaction notes

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