Sodium Hydroxide → HCID 67212115, compound

Participants

Reaction Conditions

Reaction Steps

Sodium hydroxide (39 mg, 1.0 mmol) was added to a suspension of 3-(2-fluoro-4-iodo-phenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid ethyl ester (400 mg, 0.91 mmol) in IMS (6 ml) and the reaction heated at 60° C. for 5 hours. The reaction mixture was concentrated in vacuo to yield the title compound as a yellow solid (439 mg, 100%). LCMS (method B): RT=2.19 min, M-Na+H+=412.

Provenance & Evidence