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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 226531Generated: October 30, 2026

2-(5-Hydroxy-4'-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl ester → HCID 57754935, compound

https://huagongshe.com/reaction/226531

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(5-Hydroxy-4'-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl esterHCID 57754941—
ReactantHCID 178505688HCID 178505688—
ProductHCID 57754935HCID 5775493510%

Reaction Steps

The title compound was prepared in 10% yield from 2-(5-hydroxy-4′-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl ester (prepared in Example 15, step (f)) and 3-fluoro,5-trifluoromethylbenzene boronic acid under the conditions described in Example 15, step (g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557244B2
Source datasetuspto-grants-2009_07
ORD IDord-9a047b47fe834646bdec78d64420d2e5
Source noteuspto-grants-2009_07