2-Amino-5-methylpyridine → HCID 17854370, compound

HRID 2265326Notes

Reaction equation

HRID 2265326 reaction equation
[CH2:1]([O:8][C:9]1[CH:18]=[CH:17][CH:16]=[C:15]2[C:10]=1[CH2:11][CH2:12][CH2:13][CH:14]2[C:19]([OH:21])=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:22][C:23]1[CH:28]=[CH:27][C:26]([CH3:29])=[CH:25][N:24]=1>>[CH2:1]([O:8][C:9]1[CH:18]=[CH:17][CH:16]=[C:15]2[C:10]=1[CH2:11][CH2:12][CH2:13][CH:14]2[C:19]([NH:22][C:23]1[CH:28]=[CH:27][C:26]([CH3:29])=[CH:25][N:24]=1)=[O:21])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 153482-Amino-5-methylpyridineHCID 112083185-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid

Product 1

HCID 17854370HCID 17854370, compoundYield 53.8%

Procedure

By the reaction and treatment in the same manner as in Preparation Example 11 using 5-benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (2.82 g) and 2-amino-5-methylpyridine (1.08 g) as starting materials, 5-benzyloxy-N-(5-methylpyridin-2-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (2.00 g) was obtained.

Workup

  1. customBy the reaction and treatment in the same manner

Sources & evidence

ORD record
ord-6e6c5f3f5914452e91bfb954983e8c51
Source dataset
uspto-grants-2010_12
Patent number
US07855297B2

Reaction notes

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