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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2265429Generated: October 26, 2026

1,2,3,4-Tetrahydro-1-naphthoic acid → N-[(5-ethylthiophen-2-yl) methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide

https://huagongshe.com/reaction/2265429

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2,3,4-Tetrahydro-1-naphthoic acidHCID 12598146—
Reactant[(5-Ethylthiophen-2-yl)methyl](4-isopropylphenyl)amineHCID 29282954—
ProductN-[(5-ethylthiophen-2-yl) methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamideHCID 1667966210.9%

Reaction Steps

By the reaction and treatment in the same manner as in Example 12 using 1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.7 g) and [(5-ethylthiophen-2-yl)methyl](4-isopropylphenyl)amine (1.04 g) as starting materials, N-[(5-ethylthiophen-2-yl) methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.18 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07855297B2
Source datasetuspto-grants-2010_12
ORD IDord-b6edba0d841e4e5f9de71c61c45af780
Source noteuspto-grants-2010_12