HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Bromo-1-chloro-2-(chloromethyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (5-Bromo-2-chlorophenyl)methanol | HCID 5074766 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Bromo-1-chloro-2-(chloromethyl)benzene | HCID 43379070 | — |
Reaction Steps
A solution of 4-bromo-1-chloro-2-hydroxymethyl-benzene (40.0 g) and thionyl chloride (60 mL) in dichloromethane (150 mL) is stirred at 45-50° C. for 5 h. Then the solvent and the excess reagent is removed in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858587B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-634b9fe7937d48c49f48cb0e27cac218 |
| Source note | uspto-grants-2010_12 |