HCID 178500713, compound → HCID 178500712, compound

HRID 2265917Notes

Reaction equation

HRID 2265917 reaction equation
[CH3:1][O:2][C:3](=[O:18])[CH2:4][C@H:5]1[CH2:8][C@H:7]([CH2:9][O:10]CC2C=CC=CC=2)[CH2:6]1>C(OC(=O)C)C.[Pd]>[CH3:1][O:2][C:3](=[O:18])[CH2:4][C@H:5]1[CH2:8][C@H:7]([CH2:9][OH:10])[CH2:6]1

Participants

4

Reactant 1

HCID 178500713HCID 178500713, compound

Product 1

HCID 178500712HCID 178500712, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

Prepared from trans-(3-benzyloxymethyl-cyclobutyl)-acetic acid methyl ester (980 mg, 3.95 mmol) by hydrogenation 16 hours at room temperature using Pd/C (10%) (420 mg) in ethylacetate (20 ml).

Sources & evidence

ORD record
ord-584d5ebb0337458596a05308a7f54cfa
Source dataset
uspto-grants-2010_12
Patent number
US07858630B2

Reaction notes

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