HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[4-(aminomethyl)-2-fluorophenyl]methanesulfonamide hydrochloride → HCID 59598182, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[4-(aminomethyl)-2-fluorophenyl]methanesulfonamide hydrochloride | HCID 21097525 | — |
| Reactant | 1005171-56-1 | HCID 66665123 | — |
| Product | HCID 59598182 | HCID 59598182 | 88% |
Reaction Steps
N-(4-Aminomethyl-2-fluoro-phenyl)-methanesulfonamide HCl salt (270 mg, 1.00 mmol) was reacted with (6-trifluoromethyl-pyridin-3-yloxy)-acetic acid (221 mg) to give N-(3-fluoro-4-methanesulfonylamino-benzyl)-2-(6-trifluoromethyl-pyridin-3-yloxy)-acetamide (54 mg, 88%) after recrystallization from Hex/EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858621B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-745ff53df6f54de88e70b4290054ec48 |
| Source note | uspto-grants-2010_12 |