HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → 3-(2-Chloro-6-trifluoromethyl-pyridin-3-yl)-acrylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 86625525 | HCID 86625525 | — |
| Product | 3-(2-Chloro-6-trifluoromethyl-pyridin-3-yl)-acrylic acid | HCID 72335632 | 99.8% |
Reaction Steps
3-(2-Chloro-6-trifluoromethyl-pyridin-3-yl)-acrylic acid methyl ester (200 mg, 0.753 mmol) was reacted with 0.5N-LiOH (2 eq) to give 3-(2-chloro-6-trifluoromethyl-pyridin-3-yl)-acrylic acid (189 mg, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858621B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-bbf8297716024f8fb9dc331e48c298be |
| Source note | uspto-grants-2010_12 |