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HRID2265998

反应详情

EQUATION

反应方程式

HRID 2265998 的结构方程式

REACTANTS

反应物

2
结构：CCC(C)Oc1nc(C(F)(F)F)ccc1C=CC(=O)O
HCID68780684

未命名化合物

结构：C=Cc1cc(CN)cc(F)c1NS(C)(=O)=O.Cl
HCID68785944

未命名化合物

PRODUCTS

生成物

1
结构：C#Cc1cc(CNC(=O)C=Cc2ccc(C(F)(F)F)nc2OC(C)CC)cc(F)c1NS(C)(=O)=O
HCID74382620

未命名化合物

收率 25.6%

PROCEDURE

实验过程

N-(4-Aminomethyl-2-ethenyl-6-fluoro-phenyl)-methanesulfonamide HCl salt (35 mg, 0.13 mmol) was reacted with 3-(2-sec-butoxy-6-trifluoromethyl-pyridin-3-yl)-acrylic acid (22 mg) to give the title compound (10 mg) after purification by column chromatography (Hex/EtOAc=1/1).