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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2265998Generated: October 26, 2026

3-(2-sec-Butoxy-6-trifluoromethyl-pyridin-3-yl)-acrylic acid → HCID 74382620, compound

https://huagongshe.com/reaction/2265998

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-sec-Butoxy-6-trifluoromethyl-pyridin-3-yl)-acrylic acidHCID 68780684—
ReactantHCID 68785944HCID 68785944—
ProductHCID 74382620HCID 7438262025.6%

Reaction Steps

N-(4-Aminomethyl-2-ethenyl-6-fluoro-phenyl)-methanesulfonamide HCl salt (35 mg, 0.13 mmol) was reacted with 3-(2-sec-butoxy-6-trifluoromethyl-pyridin-3-yl)-acrylic acid (22 mg) to give the title compound (10 mg) after purification by column chromatography (Hex/EtOAc=1/1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858621B2
Source datasetuspto-grants-2010_12
ORD IDord-8db7cfc6e53941388104a8f50060aab3
Source noteuspto-grants-2010_12