HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 2-(6-Isopropyl-1,3-dimethyl-1H-indol-5-yloxy)-4-methoxy-but-2-enenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | (6-Isopropyl-1,3-dimethyl-1H-indol-5-yloxy)-acetonitrile | HCID 59598566 | — |
| Product | 2-(6-Isopropyl-1,3-dimethyl-1H-indol-5-yloxy)-4-methoxy-but-2-enenitrile | HCID 67053406 | — |
Reaction Steps
2-(6-Isopropyl-1,3-dimethyl-1H-indol-5-yloxy)-4-methoxy-but-2-enenitrile was prepared from (6-isopropyl-1,3-dimethyl-1H-indol-5-yloxy)-acetonitrile by treatment with sodium hydride and methyl iodide using the procedure of step 6 of Example 2 above.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858632B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-aae4b7be19524ad3aeabda7e8d679f17 |
| Source note | uspto-grants-2010_12 |