HCID 3707209, compound → HCID 86631446, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-(2,4-dichlorobenzyl)-3-oxobutyric acid ethyl ester (4.6 g) and 3-amino-4-fluorophenol (1.0 g) was heated by microwave irradiation at 120° C. for 20 minutes. The mixture was purified by column chromatography on silica gel, eluting with a mixture of ethyl acetate and pentane (1:19 to 1:1 by volume) to afford title compound, 0.67 g.

Provenance & Evidence