Ethanol → N-(5-amino-2-fluorophenyl)acetamide(SALTDATA: 0.95HCl 0.8H2O)

Participants

Reaction Steps

A mixture of 2-fluoro-5-nitrophenylamine (2.0 g), palladium, 10 wt. % on activated carbon (0.10 g) and ethanol (20 mL) were stirred at room temperature for 2 hours under an atmosphere of hydrogen. The mixture was filtered through hyflo, washing with ethanol and the solvent removed under reduced pressure to afford title compound as a white solid, 1.7 g.

Provenance & Evidence