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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2266571Generated: October 26, 2026

Butanethioic acid, 3-oxo-, S-(1,1-dimethylethyl) ester → 2-(4-chloro-2-fluorobenzyl)-3-oxothiobutyric acid S-tert-butyl Ester

https://huagongshe.com/reaction/2266571

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButanethioic acid, 3-oxo-, S-(1,1-dimethylethyl) esterHCID 140007—
Reactant4-Chloro-2-fluorobenzyl bromideHCID 2736551—
Product2-(4-chloro-2-fluorobenzyl)-3-oxothiobutyric acid S-tert-butyl EsterHCID 86631451—

Reaction Steps

The title compound was prepared by the method of Preparation 34a using 1-bromomethyl-4-chloro-2-fluorobenzene and 3-oxothiobutyric acid S-tert-butyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858640B2
Source datasetuspto-grants-2010_12
ORD IDord-ac32139d5d2d4d0695f91b26a7887aba
Source noteuspto-grants-2010_12