HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-4-fluorophenol → 2-(2-chloro-4-fluorobenzyl)-N-(2-fluoro-5-hydroxyphenyl)-3-oxobutyramide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-4-fluorophenol | HCID 13519180 | — |
| Reactant | 2-(2-chloro-4-fluorobenzyl)-3-oxothiobutyric acid S-tert-butyl Ester | HCID 86631454 | — |
| Product | 2-(2-chloro-4-fluorobenzyl)-N-(2-fluoro-5-hydroxyphenyl)-3-oxobutyramide | HCID 86631455 | — |
Reaction Steps
The title compound was prepared by the method of Preparation 34b using 3-amino-4-fluorophenol and 2-(2-chloro-4-fluorobenzyl)-3-oxothiobutyric acid S-tert-butyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858640B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-82fd6ba868094685b2e4c4b97ec7b464 |
| Source note | uspto-grants-2010_12 |