HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Amino-4-fluorophenoxy)acetic acid methyl ester → {3-[2-chloro-4-(pyrrolidine-1-carbonyl)benzyl]-2-ethyl-8-fluoro-4-oxo-1,4-dihydroquinolin-5-yloxy}acetic Acid Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Amino-4-fluorophenoxy)acetic acid methyl ester | HCID 66717607 | — |
| Reactant | 2-[2-chloro-4-(pyrrolidine-1-carbonyl)benzyl]-3-oxopentanoic Acid Ethyl Ester | HCID 68784675 | — |
| Product | {3-[2-chloro-4-(pyrrolidine-1-carbonyl)benzyl]-2-ethyl-8-fluoro-4-oxo-1,4-dihydroquinolin-5-yloxy}acetic Acid Methyl Ester | HCID 68783901 | — |
Reaction Steps
The title compound was prepared by the method of Preparation 65c using 2-[2-chloro-4-(pyrrolidine-1-carbonyl)benzyl]-3-oxopentanoic acid ethyl ester and (3-amino-4-fluorophenoxy)acetic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858640B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-c3cb77b2bdab4992ae5d8ea62fef2596 |
| Source note | uspto-grants-2010_12 |