Trifluoroacetic acid → HCID 57877632, compound

Participants

Reaction Steps

1-[(Benzyloxy)carbonyl]-4-(2-naphthyl)piperidine-4-carboxylic acid To a solution of 1.60 g (3.59 mmol) of Intermediate 9 in 10 mL of anhydrous dichloromethane was added 10 mL of trifluoroacetic acid. The resulting mixture was stirred at ambient temperature for 2 h and then all volatiles were removed in vacuo. The resulting residue was dissolved in 15 mL of anhydrous toluene and all volatiles were again removed in vacuo to afford the title compound as a white solid. LC/MS 390.2 (M+1).

Provenance & Evidence