HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromopyridine-2-carbonitrile → 5-(4-(Hydroxymethyl)phenylthio)picolinonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromopyridine-2-carbonitrile | HCID 817154 | — |
| Reactant | (4-Sulfanylphenyl)methanol | HCID 4677905 | — |
| Product | 5-(4-(Hydroxymethyl)phenylthio)picolinonitrile | HCID 68539292 | 28.4% |
Reaction Steps
Using the method of Preparation 155 using (4-mercaptophenyl)methanol (10.0 g, 71.3 mmol) and 5-bromopicolinonitrile (13.0 g, 71.3 mmol) affords the title compound (4.90 g, 28%).): 243 (M+H, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858646B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-6070c006cad640c9b36bf0edf7932479 |
| Source note | uspto-grants-2010_12 |