Toluene → HCID 68430182, compound

HRID 2267138Notes

Reaction equation

HRID 2267138 reaction equation
[N-:1]=[N+:2]=[N-:3].C[Si]([CH2:8][CH2:9][O:10][C:11]#[CH:12])(C)C.[C:13]1(C)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[CH2:9]([O:10][C:11]1[N:3]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[N:2]=[N:1][CH:12]=1)[CH3:8]

Participants

4

Reactant 3

HCID 1140TolueneHCID 33558AzideHCID 11309575HCID 11309575, compound

Product 1

HCID 68430182HCID 68430182, compound

Procedure

The azide substance prepared in 1) of Example 7 and (trimethylsilyl)ethoxyacetylene were dissolved in 3.0 ml of toluene and the solution was stirred for one night under heating to reflux. After the reaction solution was cooled down to room temperature, the residue was separate and purified by a silica gel column chromatography (hexane/ethyl acetate=1/1) to give 98 mg of the title compound.

Workup

  1. temperatureunder heating to reflux
  2. customthe residue was separate
  3. custompurified by a silica gel column chromatography (hexane/ethyl acetate=1/1)

Sources & evidence

ORD record
ord-c07cc9e600ed46d591a9974d66861e75
Source dataset
uspto-grants-2010_12
Patent number
US07858800B2

Reaction notes

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