HCID 58945825, compound → HCID 11545033, compound

HRID 2267160Notes

Reaction equation

HRID 2267160 reaction equation
[Cl:1][C:2]1[C:7]([N:8]2[C:12]([CH3:13])=[C:11]([C:14]3[CH2:15][CH2:16][N:17]([C:20]([O:22][C:23](C)([CH3:25])[CH3:24])=[O:21])[CH2:18][CH:19]=3)[N:10]=[N:9]2)=[CH:6][CH:5]=[CH:4][N:3]=1>Cl>[Cl:1][C:2]1[C:7]([N:8]2[C:12]([CH3:13])=[C:11]([C:14]3[CH2:15][CH2:16][N:17]([C:20]([O:22][CH:23]([CH3:25])[CH3:24])=[O:21])[CH2:18][CH:19]=3)[N:10]=[N:9]2)=[CH:6][CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 1

HCID 58945825HCID 58945825, compound

Product 1

HCID 11545033HCID 11545033, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

tert-Butyl 4-[1-(2-chloropyridin-3-yl)-5-methyl-1H-[1,2,3]-triazol-4-yl]-1,2,3,6-tetrahydropyridine-1-carboxylate (265 mg) prepared in Example 12 was dissolved in 4.0 ml of a 10% methanolic hydrochloric acid and stirred for 2.5 hours and the solvent was evaporated in vacuo to give the title compound as a mixture.

Workup

  1. customthe solvent was evaporated in vacuo

Sources & evidence

ORD record
ord-50098e9ca1a840a2b98dbd4076ad5ce3
Source dataset
uspto-grants-2010_12
Patent number
US07858800B2

Reaction notes

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