Lithium Hydroxide → HCID 57807494, compound

Participants

Reaction Steps

Prepared analogously to Example 22.1 from 80.0 mg (0.10 mmol) ethyl(S)-1-{(R)-3-(4-amino-3-chloro-5-trifluoromethyl-phenyl)-2-[4-(2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidine-1-carbonyloxy]-propionyl}-4-(1-methyl-piperidin-4-yl)-piperazine-2-carboxylate and 0.46 mL (0.23 mmol) 0.5 M LiOH solution.

Provenance & Evidence