HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → HCID 11663514, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | 1,4-Butanediol | HCID 8064 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-{1-[(3-chloropropyl)sulfonyl]-4-piperidinyl}-5-phenyl-1H-indole-7-carboxamide | HCID 59003280 | — |
| Product | HCID 11663514 | HCID 11663514 | 20.4% |
Reaction Steps
Following the general procedure of example 159, 3-{1-[(3-chloropropyl)sulfonyl]-4-piperidinyl}-5-phenyl-1H-indole-7-carboxamide (40.0 mg, 0.087 mmol), 1,4-butanediol (90 mg, 0.87 mmol), K2CO3 (35.0 mg, 0.35 mmol) and sodium iodide (0.5 mg) were reacted to give the title compound (9.1 mg, 20.4%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858796B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-3cceff9f43054a0190804bb1ac623b10 |
| Source note | uspto-grants-2010_12 |