HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 59003295, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 5-Phenyl-3-(4-piperidinyl)-1H-indole-7-carboxamide | HCID 11427162 | — |
| Reactant | 5-(3-Isoxazolyl)-3-thiophenesulfonyl chloride | HCID 86232186 | — |
| Product | HCID 59003295 | HCID 59003295 | — |
Reaction Steps
Following the general procedure in example 267, 5-(phenyl)-3-(4-piperidinyl)-1H-indole-7-carboxamide (32 mg, 0.1 mmol), 5-(3-isoxazolyl)-3-thiophenesulfonyl chloride (37.5 mg, 0.15 mmol) and triethylamine (0.06 mL, 0.3 mmol) were reacted to form the desired product which was purified by Gilson HPLC (CH3CN/Water, 0.1% TFA) (11.7 mg, 22%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858796B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-3c8f89e87cc44f57aa2ea4a8b5146d30 |
| Source note | uspto-grants-2010_12 |