HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 59003348, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Dimethyl-1,3-thiazole-5-sulfonyl chloride | HCID 2776248 | — |
| Reactant | 5-Phenyl-3-(4-piperidinyl)-1H-indole-7-carboxamide | HCID 11427162 | — |
| Product | HCID 59003348 | HCID 59003348 | — |
Reaction Steps
Following the general procedure in example 267, 5-phenyl-3-(4-piperidinyl)-1H-indole-7-carboxamide (32 mg, 0.1 mmol), 2,4-dimethyl-1,3-thiazole-5-sulfonyl chloride (24.8 mg, 0.15 mmol) and triethylamine (0.06 mL, 0.3 mmol) were reacted to form the desired product which was purified by Gilson HPLC (CH3CN/Water, 0.1% TFA) (12.7 mg, 26%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858796B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-a7dcfc659d384a09a12b7236b23168b9 |
| Source note | uspto-grants-2010_12 |