HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 59003307, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-methyl-1H-imidazole-4-sulfonyl chloride | HCID 2736887 | — |
| Reactant | 3-(4-piperidinyl)-5-(3-thienyl)-1H-indole-7-carboxamide | HCID 59600664 | — |
| Product | HCID 59003307 | HCID 59003307 | — |
Reaction Steps
Following the general procedure in example 267, 3-(4-piperidinyl)-5-(3-thienyl)-1H-indole-7-carboxamide (40 mg, 0.12 mmol), 1-methyl-1H-imidazole-4-sulfonyl chloride (29.7 mg, 0.18 mmol) and triethylamine (0.05 mL, 0.36 mmol) were reacted to form the desired product which was purified by Gilson HPLC (CH3CN/Water, 0.1% TFA) (20 mg, 34%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858796B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-1dc31337a80b406c9dc68dd6656e4f86 |
| Source note | uspto-grants-2010_12 |