Furfural → HCID 49793332, compound

HRID 2267653Notes

Reaction equation

HRID 2267653 reaction equation
[CH2:1]([O:8][C:9]([NH:11]/[C:12](=[CH:17]\[C:18]1S[CH:20]=[CH:21][CH:22]=1)/[C:13]([O:15][CH3:16])=[O:14])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C1C=C(C=O)[O:25]C=1>>[CH2:1]([O:8][C:9]([NH:11]/[C:12](=[CH:17]\[C:18]1[O:25][CH:20]=[CH:21][CH:22]=1)/[C:13]([O:15][CH3:16])=[O:14])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7362FurfuralHCID 15184928HCID 15184928, compound

Product 1

HCID 49793332HCID 49793332, compound

Procedure

A method similar to that used for the preparation of (99a) was used except that 2-furylcarboxaldehyde (288 mg) was used as the aldehyde component to afforded the desired product (530 mg). 1H NMR (300 MHz, CDCl3) δ 3.788 (s, 3H), 5.17 (s, 2H), 6.29 (m, 1H), 6.46 (m, 1H), 6.73 (br., 1H), 6.94 (s, 1H), 7.37 (m, 6H). LC/MS: 2.27 min.

Sources & evidence

ORD record
ord-a706cd24fd344a1eb22ead423384190c
Source dataset
uspto-grants-2010_12
Patent number
US07858776B2

Reaction notes

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