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HRID2267681

反应详情

EQUATION

反应方程式

HRID 2267681 的结构方程式

REACTANTS

反应物

4
结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：C[C@H]1CCCCN1
HCID6427443

(2S)-2-Methylpiperidine

C6H13N

结构：C[P+](C)(C)CC#N.[I-]
HCID10514344

(Cyanomethyl)(trimethyl)phosphanium iodide

C5H11INP

结构：CC(C)(C)OC(=O)NC1CCN(CCO)CC1
HCID45076484

tert-Butyl [1-(2-hydroxyethyl)piperidin-4-yl]carbamate

C12H24N2O3

PRODUCTS

生成物

1
结构：C[C@H]1CCCCN1CCN1CCC(NC(=O)OC(C)(C)C)CC1
HCID66841611

未命名化合物

PROCEDURE

实验过程

It is prepared analogously to 9 starting from tert-butyl ester 8 (2 g, 8.19 mmol), (S)-2-methyl-piperidine (0.985 ml, 8.19 mmol), DIEA (1.8 ml, 10.65 mmol) and cyanomethyl-trimethyl-phosphonium iodide (2.39 g, 9.83 mmol).