反应详情

The mother liquor of 17 from above is treated with 1N—NaOH to obtain the free base which is then crystallized with D-(+)-O,O′-Dibenzoyl tartaric acid as described above to give the antipode 20.

1. customto obtain the free base which
2. customis then crystallized with D-(+)-O,O′-Dibenzoyl tartaric acid
3. customto give the antipode 20