HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → (3R,4R)-3-methylpiperidin-4-yl pivalate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 59600241 | HCID 59600241 | — |
| Product | (3R,4R)-3-methylpiperidin-4-yl pivalate | HCID 59600263 | — |
Reaction Steps
The mother liquor of 17 from above is treated with 1N—NaOH to obtain the free base which is then crystallized with D-(+)-O,O′-Dibenzoyl tartaric acid as described above to give the antipode 20.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858781B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-857af50727a54a0888e06582c994aa87 |
| Source note | uspto-grants-2010_12 |