Hydrochloric Acid → HCID 46736401, compound

HRID 2267724Notes

Reaction equation

HRID 2267724 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][CH2:11][N:12]2[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]2)=[CH:6][CH:5]=1)([O-])=O.[ClH:19]>[Pd].C(O)C>[ClH:19].[ClH:19].[N:12]1([CH2:11][CH2:10][C:7]2[CH:8]=[CH:9][C:4]([NH2:1])=[CH:5][CH:6]=2)[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 10634297HCID 10634297, compound

Product 1

HCID 46736401HCID 46736401, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Compound 71 (9.1 g, 36.65 mmol) is hydrogenated for 3 h at room temperature with palladium on carbon in 150 ml of ethanol and 18.3 ml of 4M aqueous hydrochloric acid. The mixture is filtered over celite and evaporated.

Workup

  1. filtrationThe mixture is filtered over celite
  2. customevaporated

Sources & evidence

ORD record
ord-67806e0ca1744a6e950e565a71680247
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

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