Selenium Dioxide → HCID 82410987, compound

HRID 2267844Notes

Reaction equation

HRID 2267844 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[C:9]([CH3:12])=[CH:10][O:11][C:7]=2[CH:6]=[CH:5][CH:4]=1.[Se](=O)=[O:14]>O1CCOCC1>[CH3:1][O:2][C:3]1[C:8]2[C:9]([CH:12]=[O:14])=[CH:10][O:11][C:7]=2[CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 24007Selenium DioxideHCID 66842179HCID 66842179, compound

Product 1

HCID 82410987HCID 82410987, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

To a solution of 4-methoxy-3-methyl-benzofuran (J. Chem. Res. Synopses (1996), 132) (4 g, 24.66 mmol) in 40 ml of dioxane is added selenium dioxide (3.39 g, 29.59 mmol) and the mixture is heated under reflux for 24 hours. It is then cooled and filtered. The solvent is evaporated and the crude red solid is used as such in the next step.

Workup

  1. temperaturethe mixture is heated
  2. temperatureunder reflux for 24 hours
  3. temperatureIt is then cooled
  4. filtrationfiltered
  5. customThe solvent is evaporated

Sources & evidence

ORD record
ord-4dd2f9e57f814214b9b2a8e39b68e93b
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

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