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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267853Generated: October 31, 2026

HCID 66841507, compound → 4-(4,6-Dimethoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[2-((3S,4S)-4-hydroxy-3-methyl-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amide dihydrochloride

https://huagongshe.com/reaction/2267853

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66841507HCID 66841507—
Reactant(3S,4S)-1-[2-(4-Amino-piperidin-1-yl)-ethyl]-3-methyl-piperidin-4-ol trihydrochlorideHCID 66841748—
Product4-(4,6-Dimethoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[2-((3S,4S)-4-hydroxy-3-methyl-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amide dihydrochlorideHCID 66841527—

Reaction Steps

This compound is synthesized from 4-(4,6-dimethoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid (126, see example 99) and amine 14 analogously to the method described in example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-da50ef41115845bcbc2e44dba316756f
Source noteuspto-grants-2010_12