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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267862Generated: October 30, 2026

HCID 66841346, compound → 4-(4-Methoxy-phenyl)-1H-indole-2-carboxylic acid {1-[(S)-2-(4-hydroxy-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide

https://huagongshe.com/reaction/2267862

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66841346HCID 66841346—
Reactant1-[(S)-2-(4-Amino-piperidin-1-yl)-1-methyl-ethyl]-piperidin-4-ol trihydrochlorideHCID 66841433—
Product4-(4-Methoxy-phenyl)-1H-indole-2-carboxylic acid {1-[(S)-2-(4-hydroxy-piperidin-1-yl)-propyl]-piperidin-4-yl}-amideHCID 59600186—

Reaction Steps

This compound is synthesized analogously to example 1 from 4-(4-methoxy-phenyl)-1H-indole-2-carboxylic acid, 128 (see example 141) and amine 50.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-8b30265adcc14f05ace6fb43a0c2fc1e
Source noteuspto-grants-2010_12