4-(5-Methyl-2-nitro-phenoxy)-1H-indole-2-carboxylic acid ethyl ester → 4-(2-Amino-5-methyl-phenoxy)-1H-indole-2-carboxylic acid ethyl ester

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Reaction Steps

134 (1.3 g, 3.82 mmol) is dissolved in 250 ml of ethyl acetate and, after addition of Pd—C (200 mg), the mixture is hydrogenated at room temperature for 3 hours. The mixture is filtrated over celite to remove the catalyst and evaporated.

Provenance & Evidence