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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267902Generated: October 26, 2026

(1-Methyl-3-piperidyl)methanol → 4-Isobutoxy-1H-indole-2-carboxylic acid [1-(1-methyl-piperidin-3-ylmethyl)-piperidin-4-yl]-amide

https://huagongshe.com/reaction/2267902

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1-Methyl-3-piperidyl)methanolHCID 97998—
Reactant4-Isobutoxy-1h-indole-2-carboxylic acid [1-(octahydro-quinolizin-1-ylmethyl)-piperidin-4-yl]-amide dihydrochlorideHCID 131728603—
Product4-Isobutoxy-1H-indole-2-carboxylic acid [1-(1-methyl-piperidin-3-ylmethyl)-piperidin-4-yl]-amideHCID 59600123—

Reaction Steps

This compound is synthesized from the compound 161 (see example 127) and (1-Methyl-piperidin-3-yl)-methanol analogously to the method described in Example 127.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-f7e2e65ed20241e49cd8ad6eb88ea50a
Source noteuspto-grants-2010_12