HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-1,2-Epoxypropane → HCID 66841456, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-1,2-Epoxypropane | HCID 146261 | — |
| Reactant | (3R,4R)-3-methylpiperidin-4-yl pivalate | HCID 59600263 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 66841456 | HCID 66841456 | — |
Reaction Steps
A solution of piperidine 20 (3 g, 15.05 mmol) and (R)-2-methyl-oxirane (15.05 ml, 150.5 mmol) in 10 ml of ethanol is stirred for 24 hours in a closed flask. The solvent is evaporated and the residue distilled in a Kugelrohr apparatus (0.08 mbar, 80-90 C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858781B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-d37179dae5e44ed9b6bd8d0c2131dd92 |
| Source note | uspto-grants-2010_12 |