1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-6-iodohexane → HCID 18348353, compound

HRID 2267993Notes

Reaction equation

HRID 2267993 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4](I)[CH:3]=1.[F:9][C:10](I)([F:27])[C:11]([F:26])([F:25])[C:12]([F:24])([F:23])[C:13]([F:22])([F:21])[C:14]([F:20])([F:19])[C:15]([F:18])([F:17])[F:16]>CS(C)=O.[Cu]>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([C:10]([F:27])([F:9])[C:11]([F:25])([F:26])[C:12]([F:23])([F:24])[C:13]([F:21])([F:22])[C:14]([F:20])([F:19])[C:15]([F:18])([F:17])[F:16])[CH:3]=1

Participants

5

Reactant 2

HCID 677331,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-6-iodohexaneHCID 707251-Fluoro-3-iodobenzene

Product 1

HCID 18348353HCID 18348353, compound

Reagents, catalysts & solvents 2

HCID 23978CopperCatalystHCID 679Dimethyl SulfoxideSolvent

Procedure

1-Fluoro-3-(perfluorohexyl) benzene was prepared by heating 6.02 g 1-fluoro-3-iodobenzene and 13.3 g perfluorohexyl iodide with excess copper in dimethyl sulfoxide (DMSO) at approximately 125° C. for 24 hours. The product, 1 -fluoro-3-perfluorohexyl benzene, was obtained in good yield (10.0 g, 89%).

Sources & evidence

ORD record
ord-3abea3afc416420095381ffd05033d0e
Source dataset
uspto-grants-2001_12
Patent number
US06326337B1

Reaction notes

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